SMDB -ENSMUSG00000015839.6-

Expression Profile _(MHU-3) _MHU-1 _MHU-2 _MHU-4 _MHU-5

Graph

Grouped by Tissue

Grouped by Genotype · Environment

_{Time Point of Sampling: R+2}

_{Time Point of Sampling: R+2}

Table

Thymus

Liver

Spleen

BAT

WAT

Tp. Bone

Md. Bone

Cerebrum

Kidney

Bone Marrow

Soleus

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 24.21 23.03 20.93 24.71 25.01 21.52

WT-FL 32.52 28.03 32.34 26.09 27.84 29.90

KO-GC 7.55 7.61 9.37 11.12 11.23 9.93

KO-FL 13.38 13.21 12.75 13.33 11.38 13.58

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 41.03 37.75 34.83 43.34 57.16 43.66

WT-FL 41.80 53.51 48.34 63.34 66.15 60.82

KO-GC 13.07 16.53 13.36 15.15 17.15 17.26

KO-FL 19.61 16.75 15.64 23.54 24.10 20.93

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 85.13 74.30 73.14 76.95 73.54 79.53

WT-FL 82.85 79.90 77.31 73.93 86.67 79.74

KO-GC 67.83 65.34 67.12 61.76 60.37 65.17

KO-FL 66.07 64.69 65.29 63.51 63.02 63.47

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 35.64 37.06 39.38 36.73 37.66 40.51

WT-FL 57.08 45.01 36.57 40.48 34.63 41.41

KO-GC 11.94 11.80 12.30 16.06 15.36 16.49

KO-FL 16.47 16.72 15.88 17.30 17.38 19.02

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 82.52 74.09 87.93 75.38 58.06 76.37

WT-FL 80.60 58.71 61.39 70.90 69.28 68.21

KO-GC 35.17 31.93 25.84 40.76 38.66 31.06

KO-FL 27.17 26.96 27.56 27.91 34.27 31.00

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 73.91 68.40 65.20 60.36 55.50 73.45

WT-FL 89.11 80.42 91.89 62.75 95.05 61.09

KO-GC 28.92 27.54 36.09 25.23 18.32 24.07

KO-FL 25.10 31.86 30.15 32.92 18.36 23.39

Category Replicate 1 Replicate 2 Replicate 3

WT-GC 98.68 95.32 104.86

WT-FL 89.32 105.09 108.84

KO-GC 31.26 31.09 36.36

KO-FL 37.51 30.30 31.01

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 18.11 16.99 16.06 15.45 17.23 16.84

WT-FL 15.68 16.06 17.50 14.82 14.22 13.77

KO-GC 3.88 4.43 6.39 4.01 5.51 4.38

KO-FL 3.72 4.57 3.44 3.84 4.13 4.97

Category Replicate 1 Replicate 2 Replicate 3

WT-GC 48.64 53.81 57.65

WT-FL 58.14 70.87 60.18

KO-GC 27.15 22.04 24.60

KO-FL 28.85 34.58 29.95

Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6

WT-GC 18.65 21.91 26.06 20.99 22.96 17.05

WT-FL 18.22 11.39 12.61 27.26 21.81 20.13

KO-GC 4.07 4.59 3.6 5.19 7.18 5.19

KO-FL 2.27 3.38 2.22 3.38 4.31 2.83

Category Replicate 1 Replicate 2 Replicate 3

WT-GC 26.48 21.63 22.53

WT-FL 22.31 24.97 25.15

KO-GC 9.97 10.26 9.3
KO-FL 9.56 9.13 10.65

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	24.21	23.03	20.93	24.71	25.01	21.52
WT-FL	32.52	28.03	32.34	26.09	27.84	29.90
KO-GC	7.55	7.61	9.37	11.12	11.23	9.93
KO-FL	13.38	13.21	12.75	13.33	11.38	13.58

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	41.03	37.75	34.83	43.34	57.16	43.66
WT-FL	41.80	53.51	48.34	63.34	66.15	60.82
KO-GC	13.07	16.53	13.36	15.15	17.15	17.26
KO-FL	19.61	16.75	15.64	23.54	24.10	20.93

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	85.13	74.30	73.14	76.95	73.54	79.53
WT-FL	82.85	79.90	77.31	73.93	86.67	79.74
KO-GC	67.83	65.34	67.12	61.76	60.37	65.17
KO-FL	66.07	64.69	65.29	63.51	63.02	63.47

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	35.64	37.06	39.38	36.73	37.66	40.51
WT-FL	57.08	45.01	36.57	40.48	34.63	41.41
KO-GC	11.94	11.80	12.30	16.06	15.36	16.49
KO-FL	16.47	16.72	15.88	17.30	17.38	19.02

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	82.52	74.09	87.93	75.38	58.06	76.37
WT-FL	80.60	58.71	61.39	70.90	69.28	68.21
KO-GC	35.17	31.93	25.84	40.76	38.66	31.06
KO-FL	27.17	26.96	27.56	27.91	34.27	31.00

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	73.91	68.40	65.20	60.36	55.50	73.45
WT-FL	89.11	80.42	91.89	62.75	95.05	61.09
KO-GC	28.92	27.54	36.09	25.23	18.32	24.07
KO-FL	25.10	31.86	30.15	32.92	18.36	23.39

Category	Replicate 1	Replicate 2	Replicate 3
WT-GC	98.68	95.32	104.86
WT-FL	89.32	105.09	108.84
KO-GC	31.26	31.09	36.36
KO-FL	37.51	30.30	31.01

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	18.11	16.99	16.06	15.45	17.23	16.84
WT-FL	15.68	16.06	17.50	14.82	14.22	13.77
KO-GC	3.88	4.43	6.39	4.01	5.51	4.38
KO-FL	3.72	4.57	3.44	3.84	4.13	4.97

Category	Replicate 1	Replicate 2	Replicate 3
WT-GC	48.64	53.81	57.65
WT-FL	58.14	70.87	60.18
KO-GC	27.15	22.04	24.60
KO-FL	28.85	34.58	29.95

Category	Replicate 1	Replicate 2	Replicate 3	Replicate 4	Replicate 5	Replicate 6
WT-GC	18.65	21.91	26.06	20.99	22.96	17.05
WT-FL	18.22	11.39	12.61	27.26	21.81	20.13
KO-GC	4.07	4.59	3.6	5.19	7.18	5.19
KO-FL	2.27	3.38	2.22	3.38	4.31	2.83

Category	Replicate 1	Replicate 2	Replicate 3
WT-GC	26.48	21.63	22.53
WT-FL	22.31	24.97	25.15
KO-GC	9.97	10.26	9.3
KO-FL	9.56	9.13	10.65

Functional Annotation

Description

nuclear factor, erythroid derived 2, like 2

Gene Ontology

Biological Process

GO:0006355  regulation of transcription, DNA-templated

GO:0006954  inflammatory response

GO:0010628  positive regulation of gene expression

GO:0030194  positive regulation of blood coagulation

GO:0030968  endoplasmic reticulum unfolded protein response

GO:0034599  cellular response to oxidative stress

GO:0034976  response to endoplasmic reticulum stress

GO:0035690  cellular response to drug

GO:0036499  PERK-mediated unfolded protein response

GO:0042149  cellular response to glucose starvation

GO:0045454  cell redox homeostasis

GO:0045893  positive regulation of transcription, DNA-templated

GO:0045944  positive regulation of transcription by RNA polymerase II

GO:0045995  regulation of embryonic development

GO:0046326  positive regulation of glucose import

GO:0061396  regulation of transcription from RNA polymerase II promoter in response to copper ion

GO:1902037  negative regulation of hematopoietic stem cell differentiation

GO:1903788  positive regulation of glutathione biosynthetic process

GO:2000121  regulation of removal of superoxide radicals

GO:2000379  positive regulation of reactive oxygen species metabolic process

Cellular Component

GO:0000785  chromatin

GO:0005634  nucleus

GO:0005737  cytoplasm

GO:0005829  cytosol

GO:0032993  protein-DNA complex

Molecular Function

GO:0000980  RNA polymerase II distal enhancer sequence-specific DNA binding

GO:0001228  DNA-binding transcription activator activity, RNA polymerase II-specific

GO:0003677  DNA binding

GO:0003700  DNA-binding transcription factor activity

GO:0005515  protein binding

GO:0008134  transcription factor binding

Expression Profile _(MHU-3) _MHU-1 _MHU-2 _MHU-4 _MHU-5

_{Time Point of Sampling: R+2}

_{Time Point of Sampling: R+2}

Query

ENSMUSG00000015839.6

18024

108420

Nfe2l2

Functional Annotation

nuclear factor, erythroid derived 2, like 2

Human Orthologus Gene

About ibSLS

External Links

Expression Profile (MHU-3) MHU-1 MHU-2 MHU-4 MHU-5

Time Point of Sampling: R+2

Time Point of Sampling: R+2

Query

ENSMUSG00000015839.6

18024

108420

Nfe2l2

Functional Annotation

nuclear factor, erythroid derived 2, like 2

Human Orthologus Gene

Expression Profile _(MHU-3) _MHU-1 _MHU-2 _MHU-4 _MHU-5

_{Time Point of Sampling: R+2}

_{Time Point of Sampling: R+2}