We are now in the Decade of Space Mouse. During space travel, humans face various medical risks associated with environmental stresses, so-called space stresses. Detailed analyses using rodent models not only allow us to elucidate and avoid the risks in space, but also produce important insights for human pathology research on Earth. ibSLS is a platform that enhances data/sample sharing related to space biology. One small step for mouse opens up one giant leap for mankind.