Query

 Ensemble Gene ID

ENSMUSG00000015839.6

 Entrez Gene ID

18024

 MGI ID

108420

 Gene Symbol

Nfe2l2

Expression Profile (MHU-3) MHU-1

 Graph
 Table
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 24.21 23.03 20.93 24.71 25.01 21.52
WT-FL 32.52 28.03 32.34 26.09 27.84 29.90
KO-GC 7.55 7.61 9.37 11.12 11.23 9.93
KO-FL 13.38 13.21 12.75 13.33 11.38 13.58
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 41.03 37.75 34.83 43.34 57.16 43.66
WT-FL 41.80 53.51 48.34 63.34 66.15 60.82
KO-GC 13.07 16.53 13.36 15.15 17.15 17.26
KO-FL 19.61 16.75 15.64 23.54 24.10 20.93
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 85.13 74.30 73.14 76.95 73.54 79.53
WT-FL 82.85 79.90 77.31 73.93 86.67 79.74
KO-GC 67.83 65.34 67.12 61.76 60.37 65.17
KO-FL 66.07 64.69 65.29 63.51 63.02 63.47
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 35.64 37.06 39.38 36.73 37.66 40.51
WT-FL 57.08 45.01 36.57 40.48 34.63 41.41
KO-GC 11.94 11.80 12.30 16.06 15.36 16.49
KO-FL 16.47 16.72 15.88 17.30 17.38 19.02
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 82.52 74.09 87.93 75.38 58.06 76.37
WT-FL 80.60 58.71 61.39 70.90 69.28 68.21
KO-GC 35.17 31.93 25.84 40.76 38.66 31.06
KO-FL 27.17 26.96 27.56 27.91 34.27 31.00
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 73.91 68.40 65.20 60.36 55.50 73.45
WT-FL 89.11 80.42 91.89 62.75 95.05 61.09
KO-GC 28.92 27.54 36.09 25.23 18.32 24.07
KO-FL 25.10 31.86 30.15 32.92 18.36 23.39
Category Replicate 1 Replicate 2 Replicate 3
WT-GC 98.68 95.32 104.86
WT-FL 89.32 105.09 108.84
KO-GC 31.26 31.09 36.36
KO-FL 37.51 30.30 31.01
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 18.11 16.99 16.06 15.45 17.23 16.84
WT-FL 15.68 16.06 17.50 14.82 14.22 13.77
KO-GC 3.88 4.43 6.39 4.01 5.51 4.38
KO-FL 3.72 4.57 3.44 3.84 4.13 4.97
Category Replicate 1 Replicate 2 Replicate 3
WT-GC 48.64 53.81 57.65
WT-FL 58.14 70.87 60.18
KO-GC 27.15 22.04 24.60
KO-FL 28.85 34.58 29.95
Category Replicate 1 Replicate 2 Replicate 3 Replicate 4 Replicate 5 Replicate 6
WT-GC 18.65 21.91 26.06 20.99 22.96 17.05
WT-FL 18.22 11.39 12.61 27.26 21.81 20.13
KO-GC 4.07 4.59 3.6 5.19 7.18 5.19
KO-FL 2.27 3.38 2.22 3.38 4.31 2.83

Functional Annotation

 Description

nuclear factor, erythroid derived 2, like 2

 Gene Ontology

Biological Process

  • GO:0006355    regulation of transcription, DNA-templated  
  • GO:0006954    inflammatory response  
  • GO:0010628    positive regulation of gene expression  
  • GO:0030194    positive regulation of blood coagulation  
  • GO:0030968    endoplasmic reticulum unfolded protein response  
  • GO:0034599    cellular response to oxidative stress  
  • GO:0034976    response to endoplasmic reticulum stress  
  • GO:0035690    cellular response to drug  
  • GO:0036499    PERK-mediated unfolded protein response  
  • GO:0042149    cellular response to glucose starvation  
  • GO:0045454    cell redox homeostasis  
  • GO:0045893    positive regulation of transcription, DNA-templated  
  • GO:0045944    positive regulation of transcription by RNA polymerase II  
  • GO:0045995    regulation of embryonic development  
  • GO:0046326    positive regulation of glucose import  
  • GO:0061396    regulation of transcription from RNA polymerase II promoter in response to copper ion  
  • GO:1902037    negative regulation of hematopoietic stem cell differentiation  
  • GO:1903788    positive regulation of glutathione biosynthetic process  
  • GO:2000121    regulation of removal of superoxide radicals  
  • GO:2000379    positive regulation of reactive oxygen species metabolic process  

Cellular Component

  • GO:0000785    chromatin  
  • GO:0005634    nucleus  
  • GO:0005737    cytoplasm  
  • GO:0005829    cytosol  
  • GO:0032993    protein-DNA complex  

Molecular Function

  • GO:0000980    RNA polymerase II distal enhancer sequence-specific DNA binding  
  • GO:0001228    DNA-binding transcription activator activity, RNA polymerase II-specific  
  • GO:0003677    DNA binding  
  • GO:0003700    DNA-binding transcription factor activity  
  • GO:0005515    protein binding  
  • GO:0008134    transcription factor binding  

Human Orthologus Gene

 Ensemble Gene ID
ENSG00000116044
 Entrez Gene ID
4780
 Gene Symbol
NFE2L2
 Description
nuclear factor, erythroid 2 like 2
 Expression Profile [External Links]
  • Japanese Multi Omics Reference Panel (jMorp)
  • Genotype-Tissue Expression (GTEx)
  • Expression Atlas
  • Reference Expresssion Dataset (RefEx)